The Pixel 5 has a sizeable hole in its back panel, but JerryRigEverything has demonstrated that it is nothing to worry about. Instead, it turns out that the Pixel 5 is more resistant to being twisted and abused, despite its cut out for wireless charging. The bio-resin coating is much thicker than the coating on the Pixel 4 series, too.
https://www.notebookcheck.net/The-Google-Pixel-5-has-a-hole-for-wireless-charging-but-bio-resin-saves-the-day.507697.0.html