A company insider has told a South Korean news outlet that Samsung plans on releasing one last Galaxy Note smartphone before retiring the series entirely in 2022. The Galaxy Note 21 will come in only one variant, presumably top-of-the-line hardware like the Exynos 2100/Snapdragon 875, an AMOLED panel that can push 120Hz at 1440p, and more.
https://www.notebookcheck.net/Samsung-may-launch-one-Galaxy-Note-21-variant-before-retiring-the-series-in-2022.506741.0.html